Screening for antitumor activity of various plant extracts on HeLa and C 4-I cell lines

Ozcan G., Ozsoylemez O. D., Akman G., Khalilia W., Yetiz B. T., Karagoz A., ...Daha Fazla

JOURNAL OF BUON, cilt.21, sa.6, ss.1552-1560, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 6
  • Basım Tarihi: 2016
  • Dergi Adı: JOURNAL OF BUON
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1552-1560
  • Anahtar Kelimeler: antitumor, Centaurea antiochia, Colchicum sanguicolle, Crateagus microphylla, C 4-I, HeLa, RAPID COLORIMETRIC ASSAY, CYTOTOXIC ACTIVITIES, GROWTH, SURVIVAL
  • İstanbul Üniversitesi Adresli: Evet

Özet

Purpose: Cancer is a long process that leads the organism to death and is associated with the normal cells acquiring the ability to divide permanently. Nowadays, the use of natural products in cancer therapy has a great importance. In addition, working with plants that are endemic to Turkey and determining the biological activities of these plant extracts, is extremely important due to the potential for new drug development. There is no comparative study available in the literature on the antitumor effects of Colchicum sanguicolle, a new found species of the genus Colchicum in Turkey, Crateagus microphylla, of the genus Crateagus and Centaurea antiochia of the genus Centaurea. In this study, we tried to demonstrate the antitumor effect of these plant extracts on HeLa and C 4-1 cells.