Circulating IL-2 and IL-10 in chronic active hepatitis C with respect to the response to IFN treatment

Bozkaya H., Bozdayi A., Aslan N., Turkay C., Sarioglu M., Cetinkaya H., ...More

INFECTION, vol.28, no.5, pp.309-313, 2000 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 5
  • Publication Date: 2000
  • Doi Number: 10.1007/s150100070025
  • Journal Name: INFECTION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.309-313
  • Istanbul University Affiliated: No

Abstract

Background: The importance of circulating immunoregulatory cytokines in response to IFN treatment and the change of in vivo production of these cytokines during interferon (IFN) treatment are not well known. We aimed to determine whether pretreatment serum levels of IL-2 and IL-10 are predictive of the response to IFN treatment and to investigate if treatment response or nonresponse has any effect on the circulating levels of these cytokines.