Examining facial emotion recognition as an intermediate phenotype for psychosis: Findings from the EUGEI study

Fusar-Poli, Laura; Pries, Lotta-Katrin; van Os, Jim; Erzin, Gamze; Delespaul, Philippe; Kenis, Gunter; Luykx, Juryen; Lin, Bochao; Richards, Alexander; Akdede, Berna; Binbay, Tolga; ALTINYAZAR, VESİLE; Yalincetin, Berna; GÜMÜŞ AKAY, GÜVEM; Cihan, Burgin; Soygur, Haldun; Ulas, Halis; Cankurtaran, Eylem; Kaymak, Semra; Mihaljevic, Marina; Andric-Petrovic, Sanja; Mirjanic, Tijana; Bernardo, Miguel; Mezquida, Gisela; Amoretti, Silvia; Bobes, Julio; Saiz, Pilar; Garcia-Portilla, Maria; Sanjuan, Julio; Aguilar, Eduardo; Santos, Jose; Jimenez-Lopez, Estela; Arrojo, Manuel; Carracedo, Angel; Lopez, Gonzalo; Gonzalez-Penas, Javier; Parellada, Mara; Maric, Nadja; Atbasoglu, Cem; Ucok, Vehbi; ALPTEKİN, KÖKSAL; SAKA, MERAM; Aguglia, Eugenio; Arango, Celso; O'Donovan, Michael; Rutten, Bart; Guloksuz, Sinan

doi:10.1016/j.pnpbp.2021.110440

Examining facial emotion recognition as an intermediate phenotype for psychosis: Findings from the EUGEI study

Fusar-Poli L., Pries L., van Os J., Erzin G., Delespaul P., Kenis G., ...More

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, vol.113, 2022 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 113
Publication Date: 2022
Doi Number: 10.1016/j.pnpbp.2021.110440
Journal Name: PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Animal Behavior Abstracts, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Psycinfo, Veterinary Science Database
Keywords: Schizophrenia, Emotion, Social cognition, Schizotypal traits, Polygenic risk score, SOCIAL COGNITION, STRUCTURED INTERVIEW, UNAFFECTED SIBLINGS, POLYGENIC RISK, GENETIC RISK, SCHIZOPHRENIA, INDIVIDUALS, ASSOCIATION, RELIABILITY, IMPUTATION
Istanbul University Affiliated: Yes

Abstract

Background: Social cognition impairments, such as facial emotion recognition (FER), have been acknowledged since the earliest description of schizophrenia. Here, we tested FER as an intermediate phenotype for psychosis using two approaches that are indicators of genetic risk for schizophrenia: the proxy-genetic risk approach (family design) and the polygenic risk score for schizophrenia (PRS-SCZ).