Interstitial Mycosis Fungoides With Lichen Sclerosus-Like Clinical and Histopathological Features

Tekin B., Kempf W., SEÇKİN GENÇOSMANOĞLU D., Ergun T., Yucelten D., Demirkesen C.

AMERICAN JOURNAL OF DERMATOPATHOLOGY, cilt.38, ss.138-143, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 38 Konu: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1097/dad.0000000000000406
  • Dergi Adı: AMERICAN JOURNAL OF DERMATOPATHOLOGY
  • Sayfa Sayıları: ss.138-143

Özet

Mycosis fungoides (MF) simulates a variety of dermatologic disorders histopathologically and clinically, well deserving the designation of a great mimicker. Interstitial MF is a rare, but well-recognized histopathological variant resembling the interstitial form of granuloma annulare or the inflammatory phase of morphea. From a clinical standpoint, MF can have a wide array of manifestations, including an anecdotal presentation with lesions clinically suggestive of lichen sclerosus (LS). We herein report a 25-year-old man with a history of patch-stage MF who later developed widespread LS-like lesions histopathologically consistent with interstitial MF. In some biopsies, additional features resembling LS were discerned. We think that our case might represent a unique variant of interstitial MF presenting with LS-like lesions. The diagnostic challenge arising from this uncommon presentation is discussed together with review of the literature.