Treatment of Libman-Sacks endocarditis by combination of warfarin and immunosuppressive therapy

Sonsoz M. R., Tekin R. D., Gül A., Bugra Z., Atilgan D.

TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY, cilt.47, sa.8, ss.687-690, 2019 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 8
  • Basım Tarihi: 2019
  • Doi Numarası: 10.5543/tkda.2019.29213
  • Dergi Adı: TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.687-690
  • Anahtar Kelimeler: Antiphospholipid syndrome, immunosuppressive therapy, Libman-Sacks endocarditis, systemic lupus erythematosus, warfarin, NONBACTERIAL THROMBOTIC ENDOCARDITIS, ANTIPHOSPHOLIPID SYNDROME, FOLLOW-UP, MANAGEMENT, DIAGNOSIS
  • İstanbul Üniversitesi Adresli: Evet

Özet

Antiphospholipid syndrome (APS) is a clinical disorder that creates an increased risk of arterial or venous thrombotic events or pregnancy-associated complications and includes the presence of autoantibodies against negatively charged phospholipids. This syndrome is often associated with systemic autoimmune diseases, such as systemic lupus erythematosus (SLE). Libman-Sacks endocarditis is a form of non-bacterial thrombotic endocarditis and is infrequently seen in APS. There are few data documenting the echocardiographic response of APS valve disease to medical treatment. This is an unusual case of a young female patient with SLE and APS who had chorea and non-bacterial thrombotic aortic valve endocarditis. Echocardiography revealed that the vegetation had receded after a combination of warfarin and immunosuppressive therapy.