Clinical, virological, imaging and pathological findings in a SARS CoV-2 antibody positive cat

Ozer K., YILMAZ A., Carossino M., YÜZBAŞIOĞLU ÖZTÜRK G., ERDOĞAN BAMAÇ Ö., TALİ H. E., ...More

JOURNAL OF VETERINARY SCIENCE, vol.23, no.4, 2022 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 4
  • Publication Date: 2022
  • Doi Number: 10.4142/jvs.21310
  • Journal Name: JOURNAL OF VETERINARY SCIENCE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, Directory of Open Access Journals
  • Keywords: Cat, SARS-CoV-2, antibody, X-ray, tomography, ground -glass opacity, interstitial pneumonia
  • Istanbul University Affiliated: Yes

Abstract

This paper reports a presumptive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in a cat. A cat with respiratory disease living with three individuals with coronavirus disease 2019 showed bilateral ground-glass opacities in the lung on X-ray and computed tomography. The clinical swabs were negative for SARS-CoV-2 RNA, but the serum was positive for SARS-CoV-2 antibodies. Interstitial pneumonia and prominent type 2 pneumocyte hyperplasia were noted on histopathology. Respiratory tissues were negative for SARS-CoV-2 RNA or antigen, but the cat was positive for feline parvovirus DNA. In conclusion, the respiratory disease and associated pathology in this cat could have been due to exposure to SARS-CoV-2.