PREVENTIVE EFFECTS OF MATRIX-METALLOPROTEINASE INHIBITORS ON DENTAL EROSION


KORUYUCU M., İLİSULU S. C., SARCAN F., KURUOĞLU F., EROL A., SEYMEN F.

FLUORIDE - QUARTERLY REPORTS, vol.55, no.2, pp.11, 2022 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 55 Issue: 2
  • Publication Date: 2022
  • Journal Name: FLUORIDE - QUARTERLY REPORTS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aqualine, BIOSIS, CAB Abstracts, EMBASE, Veterinary Science Database, Directory of Open Access Journals
  • Page Numbers: pp.11
  • Istanbul University Affiliated: Yes

Abstract

The purpose of this study was to investigate the effects of Chlorhexidine (CHX) and Epigallocatechin-3-gallate (EGCG) on dental erosion. Forty-four non-carious, recently extracted human third molars were used. The 44 dental crown slabs were randomly divided into 4 groups as follows: Group 1: 1.100 ppm Sodium Fluoride (NaF), Group 2: 0.61% EGCG, Group 3: 12% CHX, Group 4: 0.2 % CHX. Samples individually immersed in 30 mL of Coke (R) for 5 days, 4 times, 1 minute a day for erosive demineralization. The samples were immersed in 1.100 Sodium Fluoride (NaF), 0.61% EGCG, 12% CHX, 0.2% CHX for 4 times, 1 minute, each day for remineralization. The changes in the dental surface were evaluated by using a stylus profiler with surface roughness (Ra values). Topographic characteristics were assessed by Scanning Electron Microscope (SEM). Mann-Whitney U, Kruskal Wallis, and Wilcoxon Signed Ranks tests were used for statistical analyses. Significant decrease was observed in the remineralization measurement of Ra values in the EGCG group when compared with the demineralization values (p < 0.05). SEM evaluation revealed that remineralization images of EGCG were observed more regularly than the other materials. With regard to topography; EGCG was found as successful as CHX and NAF in terms of turning demineralized areas into remineralized areas.