Neurofilament ELISA validation


Petzold A., Altintas A., Andreoni L., Bartos A., Berthele A., Blankenstein M. A. , ...More

JOURNAL OF IMMUNOLOGICAL METHODS, vol.352, no.1-2, pp.23-31, 2010 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 352 Issue: 1-2
  • Publication Date: 2010
  • Doi Number: 10.1016/j.jim.2009.09.014
  • Journal Name: JOURNAL OF IMMUNOLOGICAL METHODS
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.23-31
  • Keywords: Neurofilament, NfL, NF-L, NEFL, Biomarker, Validation, NEUROCHEMICAL DEMENTIA DIAGNOSTICS, CEREBROSPINAL-FLUID, ALZHEIMERS-DISEASE, MULTIPLE-SCLEROSIS, MARKERS, CSF, DEGENERATION, SUBUNIT, PROTEIN, ASSAYS

Abstract

Background: Neurofilament proteins (Nf) are highly specific biomarkers for neuronal death and axonal degeneration. As these markers become more widely used, an inter-laboratory validation study is required to identify assay criteria for high quality performance.