Clinical usefulness of mean platelet volume and red blood cell distribution width to platelet ratio for predicting the severity of hepatic fibrosis in chronic hepatitis B virus patients

Karagoz E., Ulcay A., Tanoglu A., Kara M., Turhan V., Erdem H., ...Daha Fazla

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, cilt.26, sa.12, ss.1320-1324, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 12
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1097/meg.0000000000000203
  • Dergi Adı: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1320-1324
  • Anahtar Kelimeler: chronic hepatitis B, liver fibrosis, mean platelet volume, platelet distribution width, red blood cell distribution width, LIVER FIBROSIS, CONSENSUS STATEMENT, DISEASE, INFECTION, MARKER, INDEX
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objective Hepatitis B virus infection is still one of the leading causes of cirrhosis and hepatocellular carcinoma worldwide. Liver biopsy is the gold-standard method to assess the severity of liver fibrosis, but the invasive nature of this method limits its usage. Currently, noninvasive parameters are utilized to estimate liver histology. In the present study, we aimed to investigate the relationship between the severity of fibrosis and red blood cell distribution width (RDW), platelet distribution width (PDW), mean platelet volume (MPV), and MPV and red blood cell distribution width to platelet ratio (RPR) in patients with chronic hepatitis B (CHB).