CONGENITAL MYASTHENIA GRAVIS: A CASE REPORT

Yıldız A., Gümrü Çelikel A. D.

FDI World Dental Congress, İstanbul, Türkiye, 12 - 15 Eylül 2024, ss.1, (Özet Bildiri)

  • Yayın Türü: Bildiri / Özet Bildiri
  • Basıldığı Şehir: İstanbul
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.1
  • İstanbul Üniversitesi Adresli: Evet

Özet

Congenital Myasthenia Gravis: A Case Report

Introduction:

Myasthenia Gravis (MG) is an auto-immune disorder of neuromuscular transmission affecting 15 out of 1.000.000 births which results in weakness and fatigue of skeletal muscles.The defect in neuromuscular transmission is mostly seen in the muscles of eyes,face,neck,shoulders and rarely in respiratory muscles.Anticholinesterase,corticosteroid and immunosuppressive agents are used as medications.Plasmapheresis and thymectomy are among treatment methods of MG.The aim of this study is to describe the general,skeletal,and dental findings in a patient diagnosed with MG and to discuss orthodontic treatment approaches and relapse.

Case Description:

A 19-year-old female patient was presented to our clinic with complaints of dental crowding and difficulty in chewing.In the medical history,it was determined that she was diagnosed with congenital MG at the age of 1 year.Extraoral clinical examinations revealed partial bilateral ptosis and mild hyper-nasal speech with no other functional restrictions.In intraoral examination;anterior openbite,high arched and narrow palate,Angle Class II molar relationship,severe crowding in upper arch and 6mm mandibular dental midline shift were observed.Cephalometric analysis revealed skeletal Class I relationship with maxillary transversal discrepancy,vertical growth pattern and  protrusion of upper/lower incisors.

Discussion:

The patient shows characteristic features of MG,especially in orofacial region.Dental treatments need to be planned carefully in patients with MG due to predisposing factors such as infections,stress, and medications.It should be taken into consideration that relapse may occur after orthodontic treatment due to muscle weakness.

Conclusion:

Treatment management in MG patients should include a multidisciplinary approach including surgical,radiological,genetic and neurological aspects.It is crucial for orthodontists to keep these patients under control for relapse after orthodontic treatment.

Keywords: Myasthenia Gravis, orthodontic treatment, multidisciplinary approach