Expression of MMP-1, MMP-9 and TIMP-2 in prostate carcinoma and their influence on prognosis and survival


Ozden F., Saygin C., Uzunaslan D., Onal B. , Durak H., Aki H.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, vol.139, no.8, pp.1373-1382, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 139 Issue: 8
  • Publication Date: 2013
  • Doi Number: 10.1007/s00432-013-1453-x
  • Title of Journal : JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
  • Page Numbers: pp.1373-1382

Abstract

Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) participate in tumorigenesis, and their association with disease outcome is highly controversial. The present study investigates the influence of MMP-1, MMP-9 and TIMP-2 on different clinicopathologic variables and disease-free survival (DFS) of patients with prostate carcinoma.