Akademik Veri Yönetim Sistemi
11th ConsEuro Congress, Antalya, Türkiye, 21 - 23 Nisan 2022, cilt.26, ss.7309
Aim: This in vitro study aimed to evaluate the efect of tomatine, which
is a novel matrix metalloproteinase inhibitor for dentistry, application
on diferent types of dentine as a surface pretreatment on dentine bonding strength.
Materials and Methods: The dentine surfaces of extracted molars
were fattened with a 600-grit SiC paper for a 1 min. Then, specimens
(n=84) were divided into two groups according to type of dentine as
sound (SD) and eroded (ED) (n=42). Molars in ED group were eroded
by citric acid cycling. Each group was splited into three subgroups
according to use of surface pretreatment agents (1,5 μM tomatine,
n=14; 2% chlorhexidine (CHX), n=14; control (untreated), n=14).
Buildups were incrementally constructed with microhybrid composite following three-step etch-and-rinse application. Specimens were
sectioned into sticks, and then were subjected to microtensile testing
(μTBS) after 24-h (n=7) or 6-month (n=7) of aging. Fracture surfaces
were observed under a stereomicroscope (30x magnifcation). Data
were analyzed by Student’s t test (a= 0.05).
Results: Lower μTBS values were detected in ED group. After 24-h
aging, CHX in both SD and ED groups showed lower μTBS values than
the control group (p=0.001 and p=0.061 respectively). While CHX did
not show a signifcant diference between 24-h and 6-month values in
SD (p=0.052), the highest scores were determined in all subgroups
with tomatine applications (p<0.001). Adhesive/mixed fracture type
was observed more frequently than cohesive fractures in all subgroups.
Conclusion: Tomatine was found to be a more efective MMP inhibitor than chlorhexidine in maintaining bond strength values over time.
Keywords: adhesion, chlorhexidine, eroded dentin, matrix metalloproteinase, tomatine