Efficacy and safety of donepezil in patients with Alzheimer's disease - Results of a. global, multinational, clinical experience study


Boada-Rovira M., Brodaty H., Cras P., Baloyannis S., Emre M., Zhang R., ...Daha Fazla

DRUGS & AGING, cilt.21, ss.43-53, 2004 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

Background: Donepezil has consistently been shown to be effective and well tolerated in the symptomatic treatment of Alzheimer's disease in placebo-controlled clinical trials. It has been shown to provide significant benefits in cognition, global function and activities of daily living in patients with mild-to-moderate Alzheimer's disease. However, in order to control for confounding factors, some clinical trials of donepezil have excluded patients with comorbid illness and concomitant medication use.