Ghrelin levels are decreased in non-obese prepubertal children born large for gestational age

Darendeliler F. F., Poyrazoglu Ş., Bas F., Sancakli O., Gokcay G.

EUROPEAN JOURNAL OF ENDOCRINOLOGY, vol.160, no.6, pp.951-956, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 160 Issue: 6
  • Publication Date: 2009
  • Doi Number: 10.1530/eje-08-0924
  • Journal Name: EUROPEAN JOURNAL OF ENDOCRINOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.951-956
  • Istanbul University Affiliated: Yes

Abstract

Background: Ghrelin is the natural ligand of GH secretagogue receptor. It has several metabolic functions including regulation of food intake, energy homeostasis, and body weight. An inverse relationship between fasting plasma ghrelin and insulin concentrations has been shown. Being born large for gestational age (LGA) has all increased risk of developing insulin resistance.