Crohn's disease Activity: Abdominal Computed Tomography Histopathology Correlation

Paquet N., Glickman J. N., ERTÜRK Ş. M., Ros P. R., Heverhagen J. T., Patak M. A.

EUROPEAN JOURNAL OF RADIOLOGY OPEN, vol.3, pp.74-78, 2016 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 3
  • Publication Date: 2016
  • Doi Number: 10.1016/j.ejro.2016.03.001
  • Journal Name: EUROPEAN JOURNAL OF RADIOLOGY OPEN
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Page Numbers: pp.74-78
  • Keywords: CT Crohn Small bowel Computed, Tomography, Histopathology, INFLAMMATORY-BOWEL-DISEASE, CT ENTEROGRAPHY, ABDOMINOPELVIC CT, ENTEROCLYSIS
  • Istanbul University Affiliated: No

Abstract

Purpose: Crohn's disease is a type of inflammatory bowel disease affecting estimated 4 million people worldwide. Therapy stratification of Crohn's disease (CD) is mainly based on the inflammatory activity being assessed by endoscopic biopsy and clinical criteria. Cross-sectional imaging allows for the assessment of structural characteristics of the entire gastrointestinal tract including small bowel loops and may provide potential non-invasive image-based biomarkers for the inflammatory activity of CD. The aim of this study was to explore the predictive value of Computed Tomography-based morphologic patterns for inflammatory activity in CD.