Asian Journal of Psychiatry, cilt.114, 2025 (SCI-Expanded, Scopus)
Background: The clinical high-risk (CHR) state for psychosis has been extensively studied in psychiatry. However, there remain significant gaps in the literature concerning populations in low- and middle-income countries. This is especially relevant given the sociocultural factors that influence the development of psychosis, such as childhood trauma. The present study aims to explore sociodemographic characteristics and childhood trauma among CHR individuals from Brazil, China, and Turkey, as well as to examine differences between CHR individuals and healthy controls across these countries combined. Methods: A cross-cultural sample of 253 CHR individuals and 281 healthy controls from Brazil, China, and Turkey was assessed using standardized interviews (SIPS or CAARMS) and the Childhood Trauma Questionnaire-Short Form (CTQ-SF). Sociodemographic data and CTQ scores were compared across CHR individuals from each country, and between the combined CHR group and healthy controls, to examine how childhood trauma and sociodemographic factors differ between groups. Results: CHR individuals showed significantly higher levels of childhood trauma compared to controls across nearly all trauma types, except physical neglect. Cross-country comparisons revealed notable differences: Brazilian CHR subjects had higher levels of physical abuse, emotional abuse and neglect, while Chinese CHR individuals reported more emotional neglect and physical abuse. Conclusion: Childhood trauma is highly prevalent among CHR individuals in LAMIC and varies significantly across countries, likely reflecting sociocultural differences. These findings emphasize the importance of considering cultural context in the assessment and intervention of early psychosis risk, particularly in underrepresented regions.