Serum soluble urokinase-type plasminogen activator receptor levels in male patients with acute exacerbation of schizophrenia

Genc A., Kalelioglu T., Karamustafalioglu N., Tasdemir A., Genc E. S., Akkus M., ...More

PSYCHIATRY RESEARCH, vol.236, pp.179-181, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 236
  • Publication Date: 2016
  • Doi Number: 10.1016/j.psychres.2016.01.018
  • Journal Name: PSYCHIATRY RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Page Numbers: pp.179-181
  • Istanbul University Affiliated: Yes

Abstract

Inflammatory abnormalities have been shown in the pathogenesis of schizophrenia. Soluble urokinase-type plasminogen activator receptor (suPAR) is a protein that is measurable in the circulating blood and reflects the inflammation in the body. We aimed to investigate serum suPAR levels in patients with schizophrenia who were in acute state and to compare with healthy controls. Forty five patients and 43 healthy controls were included in the study. We found no significant difference in suPAR levels between patients and controls, suggesting that suPAR as an inflammatory marker does not have a role in the inflammatory process of acute schizophrenia. (C) 2016 Elsevier Ireland Ltd. All rights reserved.