Congenital cytomegalovirus infection associated with severe lung involvement in a preterm neonate: a causal relationship?

Koklu E., Karadag A., Tunc T., ALTUN BİNGÖL D., Sarici S. U.

EUROPEAN JOURNAL OF PEDIATRICS, vol.168, no.11, pp.1409-1412, 2009 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 168 Issue: 11
  • Publication Date: 2009
  • Doi Number: 10.1007/s00431-009-0941-0
  • Journal Name: EUROPEAN JOURNAL OF PEDIATRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1409-1412
  • Keywords: Chronic lung disease, Congenital cytomegalovirus, Neonate, Pneumonitis, Preterm, Respiratory distress syndrome, VIRUS INFECTION, INFANTS, PNEUMONITIS
  • Istanbul University Affiliated: No

Abstract

We report a preterm neonate with congenital cytomegalovirus (CMV) infection associated with severe lung involvement progressing to early chronic lung disease (CLD) and death. The present case represents the earliest and the most severe lung involvement depending on recurrent maternal CMV infection reported in the literature. Neonatal mortality and progression to early CLD should be considered in the list of possible neonatal sequelae resulting from recurrent maternal CMV infection.