International real-world study of DLL3 expression in patients with small cell lung cancer

Rojo, Federico; Corassa, Marcelo; Mavroudis, Dimitrios; Oz, Ayşim; Biesma, Bonne; Brcic, Luka; Pauwels, Patrick; Sailer, Verena; Gosney, John; Miljkovic, Darko; Hader, Carlos; Wu, Meijing; Almarez, Todd; Penault-Llorca, Frederique

doi:10.1016/j.lungcan.2020.07.026

International real-world study of DLL3 expression in patients with small cell lung cancer

Rojo F., Corassa M., Mavroudis D., Oz A. B., Biesma B., Brcic L., ...More

LUNG CANCER, vol.147, pp.237-243, 2020 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 147
Publication Date: 2020
Doi Number: 10.1016/j.lungcan.2020.07.026
Journal Name: LUNG CANCER
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, EMBASE, MEDLINE
Page Numbers: pp.237-243
Istanbul University Affiliated: Yes

Abstract

Objectives: Expression of the Notch-family ligand delta-like protein 3 (DLL3), a potential therapeutic target in small cell lung cancer (SCLC), has not been assessed in the real-world setting. To identify the real-world utility of DLL3 as an SCLC therapeutic target, we performed the largest retrospective international noninterventional study to date to evaluate DLL3 prevalence in SCLC patients.