International real-world study of DLL3 expression in patients with small cell lung cancer


Rojo F., Corassa M., Mavroudis D., Oz A. B., Biesma B., Brcic L., ...Daha Fazla

LUNG CANCER, cilt.147, ss.237-243, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 147
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.lungcan.2020.07.026
  • Dergi Adı: LUNG CANCER
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.237-243
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objectives: Expression of the Notch-family ligand delta-like protein 3 (DLL3), a potential therapeutic target in small cell lung cancer (SCLC), has not been assessed in the real-world setting. To identify the real-world utility of DLL3 as an SCLC therapeutic target, we performed the largest retrospective international noninterventional study to date to evaluate DLL3 prevalence in SCLC patients.