International real-world study of DLL3 expression in patients with small cell lung cancer

Rojo, Federico; Corassa, Marcelo; Mavroudis, Dimitrios; Oz, Ayşim; Biesma, Bonne; Brcic, Luka; Pauwels, Patrick; Sailer, Verena; Gosney, John; Miljkovic, Darko; Hader, Carlos; Wu, Meijing; Almarez, Todd; Penault-Llorca, Frederique

doi:10.1016/j.lungcan.2020.07.026

International real-world study of DLL3 expression in patients with small cell lung cancer

Rojo F., Corassa M., Mavroudis D., Oz A. B., Biesma B., Brcic L., ...Daha Fazla

LUNG CANCER, cilt.147, ss.237-243, 2020 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 147
Basım Tarihi: 2020
Doi Numarası: 10.1016/j.lungcan.2020.07.026
Dergi Adı: LUNG CANCER
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, EMBASE, MEDLINE
Sayfa Sayıları: ss.237-243
İstanbul Üniversitesi Adresli: Evet

Özet

Objectives: Expression of the Notch-family ligand delta-like protein 3 (DLL3), a potential therapeutic target in small cell lung cancer (SCLC), has not been assessed in the real-world setting. To identify the real-world utility of DLL3 as an SCLC therapeutic target, we performed the largest retrospective international noninterventional study to date to evaluate DLL3 prevalence in SCLC patients.