The influence of insulin resistance on total renin level in polycystic ovary syndrome

Hacihanefioglu B., Aksu F., Karsidag K., Seyisoglu H., Elter K.

10th World Congress on Human Reproduction, Salvador, Brazil, 4 - 08 May 1999, pp.139-143 identifier

  • Publication Type: Conference Paper / Full Text
  • Volume:
  • City: Salvador
  • Country: Brazil
  • Page Numbers: pp.139-143


Purpose of this study is to determine the influence of insulin resistance on total renin with polycystic ovary syndrome (PCOS). Clinical, ultrasonographic and hormonal findings were used to define PCOS. Insulin resistance was estimated by the continuous infusion of glucose with model assessment (CIGMA) in early follicular phase. The sensitivity and specificity of the serum total renin level to diagnose women with PCOS were calculated as 80% and 71.4%, respectively. Serum total renin level which is independent from insulin resistance can be used as a diagnostic marker in normotensive women with PCOS.