Endothelial dysfunction in renal transplant patients is closely related to serum cyclosporine levels

Mercanoglu, F; Turkmen, AYDIN; Kocaman, O; Pinarbasi, B; Dursun, M; Selcukbiricik, F; Sever, MS

doi:10.1016/j.transproceed.2004.05.073

Endothelial dysfunction in renal transplant patients is closely related to serum cyclosporine levels

Mercanoglu F., Turkmen A., Kocaman O., Pinarbasi B., Dursun M., Selcukbiricik F., ...More

TRANSPLANTATION PROCEEDINGS, vol.36, no.5, pp.1357-1360, 2004 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 36 Issue: 5
Publication Date: 2004
Doi Number: 10.1016/j.transproceed.2004.05.073
Journal Name: TRANSPLANTATION PROCEEDINGS
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1357-1360
Istanbul University Affiliated: Yes

Abstract

Background. Cyclosporine (CsA), one of the standard agents used in renal transplant recipients, has been considered to cause endothelial dysfunction and to contribute to arterial complications posttransplant. Since concentration-dependent effects of CsA on endothelial functions in humans have not been examined, this study was performed to investigate this relationship.