Phytochemical analysis, antioxidant, and enzyme inhibition activity of five<i> Salvia</i> taxa from Turkey


Yilmaz G., Eruygur N., Bona G. E., BONA M., Akdeniz M., Yilmaz M. A., ...Daha Fazla

SOUTH AFRICAN JOURNAL OF BOTANY, cilt.152, ss.212-221, 2023 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 152
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1016/j.sajb.2022.11.027
  • Dergi Adı: SOUTH AFRICAN JOURNAL OF BOTANY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, CAB Abstracts, Veterinary Science Database
  • Sayfa Sayıları: ss.212-221
  • Anahtar Kelimeler: Antioxidant, Enzyme inhibition, LC-MS/MS, Phytochemical, Salvia
  • İstanbul Üniversitesi Adresli: Evet

Özet

Salvia L. species are widely used for treatment of different disorders in traditional Turkish medicine. In this study, the methanol extracts of five Salvia taxa, including S. aucheri subsp. canescens, S. aytachii, S. heldreichiana, S. viridis, and S. wiedemannii were investigated for their antioxidant activity and enzyme inhibitory potentials which are related with health-benefit properties. In addition, total phenolic and flavonoid contents were determined with Folin- Ciocalteu and aluminum chloride spectrophotometric method, respectively. Screening of enzyme inhibition activity was performed out using ELISA microplate reader. Antioxidant activity was evaluated by 2,2'-diphenyl-1-picrylhydrazyl (DPPH) and 2,2' -Azino-bis (3-ethylbenzothiazoline-6sulfonic acid) (ABTS) radical scavenging and iron chelating tests. The S. aytachii extract was found with highest total phenol content (77.82 +/- 1.76 mg PE/mg) and total flavonoid content (22.33 +/- 0.17mg QE/mg) as dry weight basis. These findings specify that the investigated Salvia taxa for anticholinesterase activity can be appealed further phytochemical estimation for spotting its active components. (c) 2022 SAAB. Published by Elsevier B.V. All rights reserved.