Antiviral properties of caffeic acid phenethyl ester and its potential application

ERDEMLI H. K. , Akyol S., Armutcu F. , Akyol O.

JOURNAL OF INTERCULTURAL ETHNOPHARMACOLOGY, vol.4, no.4, pp.344-347, 2015 (Journal Indexed in ESCI) identifier identifier

  • Publication Type: Article / Review
  • Volume: 4 Issue: 4
  • Publication Date: 2015
  • Doi Number: 10.5455/jice.20151012013034
  • Page Numbers: pp.344-347


Caffeic acid phenethyl ester (CAPE) is found in a variety of plants and well-known the active ingredient of the honeybee propolis. CAPE showed anti-inflammatory, anticarcinogenic, antimitogenic, antiviral, and immunomodulatory properties in several studies. The beneficial effects of CAPE on different health issues attracted scientists to make more studies on CAPE. Specifically, the anti-viral effects of CAPE and its molecular mechanisms may reveal the important properties of virus-induced diseases. CAPE and its targets may have important roles to design new therapeutics and understand the molecular mechanisms of virus-related diseases. In this mini-review, we summarize the antiviral effects of CAPE under the light of medical and chemical literature.