Milrinone Attenuates Heart and Lung Remote Injury Following Abdominal Aortic Cross-Clamping.

Ak E., Ak K., Ustandag U., Kervancioglu-Demirci E., Emekli-Alturfan E., Çetinel S.

Annals of vascular surgery, vol.69, pp.391-399, 2020 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 69
  • Publication Date: 2020
  • Doi Number: 10.1016/j.avsg.2020.06.050
  • Journal Name: Annals of vascular surgery
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Page Numbers: pp.391-399
  • Istanbul University Affiliated: Yes

Abstract

Background: Phosphodiesterase enzymes play a pivotal role in the pathogenesis of ischemia/reperfusion (IR). We examined the role of milrinone (MIL), a phosphodiesterase 3 inhibitor, on remote injury of the heart and lung after abdominal aortic cross-clamping.