The aim of this study was to investigate the treatment and reuse of laundry wastewater with couple of nanofiltration (NF) and reverse osmosis (RO). In the NF process, optimal values of pH, temperature, transmembrane pressure (TMP) and cross-flow rate were determined using the Taguchi L-16(4(4)) experimental design method. The smaller-the-better signal-to-noise (S/N) ratio was used to analyze the results of experiments. Flux decline caused by fouling was selected as response parameter. A pH of 8.5, temperature of 30 degrees C, TMP of 12 bar and cross-flow rate of 2 L/min were determined as optimum operating conditions in the NF process. According to analysis of variance (ANOVA), pH was the most effective factor while TMP and cross-flow rate had low effects on the fouling. Membrane fouling was also evaluated with scanning electron microscope (SEM), energy dispersive X-ray spectroscopy (EDX), zeta potential and optical profilometer measurements. In the RO process, the quality of NF permeate obtained from optimum operating conditions was improved by an RO membrane. Although a NF membrane was not effective in reducing chemical oxygen demand (COD), Orto-P and NH4+-N, these parameters were almost removed in the NF + RO system. These results showed that, the Taguchi method was successfully applied to determine the optimum operating conditions for the treatment of laundry wastewater with an NF process. Water treated with integrated membrane processes (NF + RO) is sufficient for use as laundry washing water.