In the Middle Ages, al-Andalus was one of the remarkable regions in the field of medicine in the Islamic world. Important developments flourished especially between 10^th-12^th (H. 4^th-10^th) centuries in al-Andalus. The cities became prominent in the study of medicine and many physicians were grown in those cities such as Qurtuba (Córdoba), Tulaytula (Toledo), Ishbīliya (Seville) and Girnata (Granada) for approximately eight centuries during the Islamic rule. The physicians, who synthesized the theory of the medicine and their practices, transferred their experiences and knowledge to their children; therefore, the medicine generally became a family profession. Physician Yunus b. Ahmad from Harran, who came to al-Andalus and settled in Qurtuba, and his sons Ahmad and Omar, who were famous physicians like him, were one of the early famous examples of this situation in al-Andalus. As a result of the ongoing studies in medicine in al-Andalus, the accumulation of the theory and practice was transferred within the family and certain families has emerged in the field of medicine. As a family that had educated physicians during the several generations, the family of Banū Zuhr from Ishbīliya was especially distinguished in this field among the famous families living in al-Andalus. In this context, this study aims to examine the works of the members of the Banū Zuhr family known for their medical works and their positions in the history of the Andalusian medicine.