SYNTHESIS OF SOME N,N-DISUBSTITUTED CARBAMODITHIOIC ACID-ESTERS TESTED FOR ANTIFUNGAL ACTIVITY

Ateş Ö., CESUR N., Güner H., Uzun M., Kiraz M., Kaya D.

FARMACO, cilt.50, sa.5, ss.361-364, 1995 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 50 Sayı: 5
  • Basım Tarihi: 1995
  • Dergi Adı: FARMACO
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, International Pharmaceutical Abstracts
  • Sayfa Sayıları: ss.361-364
  • İstanbul Üniversitesi Adresli: Evet

Özet

The synthesis of 12 new 4-[(N,N-disubstituted thiocarbamoylthio)acetamido]antipyrines and their antifungal activity are reported. Of these compounds, only 3e, showed good antifungal activity against C. tropicalis KUEN 1021, C. krusei KUEN 1001, C. stellatoidea KUEN 1018, C. pseudotropicalis KUEN 1012, C. albicans ATCC 10231 when compared with clotrimazole and miconazole (MIC = 12.5 mu g/ml).