Optimization of Alfuzosin HCl Tablet Formulations Using Artificial Neural Network

Mesut B., Aksu N. B., Erginer Y.

European Journal Of Pharmaceutical Sciences, vol.44, no.1, pp.93-94, 2011 (SCI-Expanded)

  • Publication Type: Article / Article
  • Volume: 44 Issue: 1
  • Publication Date: 2011
  • Journal Name: European Journal Of Pharmaceutical Sciences
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.93-94
  • Istanbul University Affiliated: Yes


In terms of content, pharmaceutical product development knowledge is very intensive and product development process is quite complex and long. Different softwares based on mathematical models have been developed In order to ease the completion of the product development process.

Recent developments in mathematics and computer science resulted in new programs based on artificial neural networks (ANN) techniques. These programs have been employed in development and formulation of pharmaceutical dosage forms (1).

In our study, Alfuzosin HCl was used as a model drug and formulations of modified release tablet forms were designed with the application of a program based on ANN technique.