Relationship of Bradykinin B-2 Receptor Gene C-58T Variation with Total-Cholesterol and Glucose in Essential Hypertension

SÜSLEYİCİ B., Gunduz M. K., Zengin S. U., Cagatay P., Bozkus H. M., Bakir N., ...More

BEZMIALEM SCIENCE, vol.5, no.1, pp.7-15, 2017 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 5 Issue: 1
  • Publication Date: 2017
  • Doi Number: 10.14235/bs.2016.738
  • Journal Name: BEZMIALEM SCIENCE
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.7-15
  • Istanbul University Affiliated: Yes

Abstract

Objective: Hypertension, which affects 25% of the world's population, is a complex disease, with 30% genes affecting its pathogenesis. In this study, we aimed to examine the frequency of the bradykinin B-2 receptor gene C-58T genotypes in patients with essential hypertension and non-hypertensive controls. In addition, we evaluated the effects of C-58T genotypes on demographic characteristics, phenotypes related to obesity, and hypertension.