Effects of Different Volatile Anesthetics on Cytokine and Chemokine Production After Ischemia-Reperfusion Injury in Patients Undergoing Living-Donor Kidney Transplant.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, cilt.17, ss.68-74, 2019 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 17
- Basım Tarihi: 2019
- Doi Numarası: 10.6002/ect.mesot2018.o10
- Dergi Adı: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.68-74
- Anahtar Kelimeler: Desflurane, Renal dysfunction, Renal transplantation, Sevoflurane, RENAL ISCHEMIA, SEVOFLURANE, VALIDATION, PROTECTION, MARKERS, CXCL10
- İstanbul Üniversitesi Adresli: Evet
Özet
Objectives: Renal transplant is the treatment of choice for patients with end-stage renal disease. Ischemia-reperfusion damage is a major cause of early renal dysfunction during the perioperative period. lschemic hypoxic damage increases local inflammation, leading to secretion of cytokines and chemokines. Anesthetic conditioning is a widely described strategy to attenuate ischemia-reperfusion injury. Here, we compared the effects of desflurane and sevoflurane on serum proinflammatory cytokines and urine chemokines in living-donor kidney transplant recipients.