Rates and associates of influenza and pneumococcus vaccination in diabetes mellitus: A nationwide cross-sectional study (TEMD vaccination study)

Demirci I., Haymana C., Salman S., Tasci I., ÇORAPÇIOĞLU D., Kirik A., ...More

WORLD JOURNAL OF DIABETES, vol.12, no.12, pp.2107-2118, 2021 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 12
  • Publication Date: 2021
  • Doi Number: 10.4239/wjd.v12.i12.2107
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), EMBASE
  • Page Numbers: pp.2107-2118
  • Keywords: Diabetes, Influenza, Pneumococcus, Vaccination, Type 1 diabetes, Type 2 diabetes, UNITED-STATES, ADULTS, IMMUNIZATION, PREDICTORS, PNEUMONIA, COVERAGE, DEATH, OLDER
  • Istanbul University Affiliated: Yes


BACKGROUNDVaccination against influenza and pneumococcus is effective in reducing morbidity and mortality in patients with diabetes.AIMTo investigate the prevalence of influenza and pneumococcal vaccinations and to search for the independent associates of vaccination in Turkish patients with diabetes.METHODSIn this cross-sectional, nationwide, multicenter study, adult patients with type 1 diabetes (T1DM) (n = 454) and type 2 diabetes (T2DM) (n = 4721), who were under follow-up for at least a year in the outpatient clinics, were consecutively enrolled. Sociodemographic, clinical, and laboratory parameters of patients were recorded. Vaccination histories were documented according to the self-statements of the patients.RESULTSPatients with T1DM and T2DM had similar vaccination rates for influenza (23.6% vs 21.2%; P = 0.240) and pneumococcus (8% vs 7%; P = 0.451) vaccinations. Longer diabetes duration and older age were the common independent associates of having vaccination for both types of diabetes patients. Higher education level, using statin treatment, and having optimal hemoglobin A1c levels were the common independent associates of influenza and pneumococcal vaccination in patients with T2DM.CONCLUSIONTEMD Vaccination Study shows that patients with T1DM and T2DM had very low influenza and pneumococcal vaccination rates in Turkey. The lower rates of vaccination in certain populations urges the necessity of nationwide vaccination strategies targeting these populations.