Lymph nodal involvement by renal angiomyolipoma

KOKSAL I., TUNC M., Kilicaslan I., ANDER H., OZCAN F., KAPLANCAN T.

INTERNATIONAL JOURNAL OF UROLOGY, vol.7, no.10, pp.386-389, 2000 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 10
  • Publication Date: 2000
  • Doi Number: 10.1046/j.1442-2042.2000.00213.x
  • Journal Name: INTERNATIONAL JOURNAL OF UROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.386-389
  • Keywords: angiomyolipoma, lymph nodal involvement, radical nephrectomy, PERIVASCULAR EPITHELIOID CELLS, TUBEROUS SCLEROSIS, SUGAR TUMOR, FAT DENSITY, CARCINOMA, LESIONS, TOMOGRAPHY, DIAGNOSIS, FEATURES, FAMILY
  • Istanbul University Affiliated: Yes

Abstract

Angiomyolipoma of the kidney is a clonal neoplasm, apparently part of a family of neoplasms derived from perivascular epithelial cells. A 40-year-old woman presented with right flank pain and an otherwise non-significant medical history. An abdominal computed tomography scan revealed an 18 cm solid mass in the mid-portion of the right kidney and multiple perihilar lymph nodes. presumptive diagnosis was renal cell carcinoma. Right radical nephrectomy and a perihilar lymph node dissection was performed through a Chevron incision for the anticipated diagnosis of renal adenocarcinoma. The renal tumor was diagnosed as angiomyolipoma and a component was identified pathologically in a dissected lymph node. There was no evidence of tumor recurrence in the follow-up period of eight years. The consensus from other studies suggests that this phenomenon is a manifestation of the multicentric nature of angiomyolipoma, rather than due to metastasis. Genetic studies may resolve this question in the future.