Electron Microscopic Comparison of Radial Artery Grafts in Non-Diabetic and Diabetic Coronary Bypass Patients

Gursoy M., Guzel E., Erturkuner P., Cakir I., Duygu E., Gulcan F., ...More

JOURNAL OF CARDIAC SURGERY, vol.31, no.7, pp.410-415, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 7
  • Publication Date: 2016
  • Doi Number: 10.1111/jocs.12761
  • Journal Name: JOURNAL OF CARDIAC SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.410-415
  • Istanbul University Affiliated: Yes

Abstract

Objective: We compared electron microscopic histologic changes of the radial artery grafts in non-diabetic and diabetic patients. Methods: Thirty-six patients were divided into three groups according to their diabetic status (Group I had no diabetes mellitus [DM], Group II had type two DM and HbA1c levels were <7.5%, and Group III had type 2 DM but HbA1c levels were >7.5%). Distal parts of radial artery grafts were evaluated with scanning electron microscopy in a blind fashion by two histologists. Electron microscopic scores were compared among the groups. Results: Radial artery electron microscopic scores were significantly different between group 1, 2 and 1, 3 and 2, 3 (p = 0.028, p<0.001, and p<0.001). In linear regression analysis, duration of DM (p = 0.027) and fasting plasma glucose (p = 0.001) were found as independent risk factors for histologic changes of radial artery grafts. Conclusion: Duration of DM and poor glycemic control were found to be associated with radial artery electron microscopic changes.