Use of topical selamectin for the treatment of Syphacia muris infection in laboratory rats

Esatgil M. U., Gulanber A., Aydin H.

POLISH JOURNAL OF VETERINARY SCIENCES, cilt.11, sa.1, ss.67-69, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 11 Sayı: 1
  • Basım Tarihi: 2008
  • Dergi Adı: POLISH JOURNAL OF VETERINARY SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.67-69
  • İstanbul Üniversitesi Adresli: Evet

Özet

Efficacy of selamectin was studied in naturally acquired S. muris infections in rats. Fourty-eight S. muris-positive rats were divided into six treated and two control groups. Selamectin (6 mg/kg) was applied topically to the skin in a single spot at the base of the neck in the treatment group. The rats of treated and control groups were necropsied on the 24th day after the treatment. Topical selamectin was found to be 40.7-63.3% effective (based on egg per gram method) in eliminating S. muris infection in rats. The efficacy of the treatment against S. muris (based on adult worm counts) in male and female rats was 35.14-58.88%, respectively (mean 48.39%).