INVOLVEMENT OF MAIN OXIDATIVE STRESS MECHANISMS IN THE TOXICITY OF BENOMYL AND CARBENDAZIM IN RATS


Catalgol S., YILMAZ B., ALPERTUNGA B.

ISTANBUL JOURNAL OF PHARMACY, vol.43, no.2, pp.103-120, 2013 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 2
  • Publication Date: 2013
  • Journal Name: ISTANBUL JOURNAL OF PHARMACY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.103-120
  • Keywords: Oxidative Stress, Benomyl, Carbendazim, Pesticide toxicity, MALE REPRODUCTIVE-SYSTEM, LIPID-PEROXIDATION, ANTIOXIDANT ENZYMES, VITAMIN-E, FUNGICIDE CARBENDAZIM, DEFENSE, LIVER, CARBAMATE, ATTENUATION, METABOLISM
  • Istanbul University Affiliated: Yes

Abstract

This study aimed to evaluate the role of oxidative stress in toxicity induced by BNL (benomyl) and its metabolite CBZ (carbendazim), which are systemic broad-spectrum benzimidazole fungicides.