Ethylene Glycol Induced Hyperoxaluria Increases Plasma and Renal Tissue Asymmetrical Dimethylarginine in Rats: A New Pathogenetic Link in Hyperoxaluria Induced Disorders

Aydin, Hasan; Yencilek, Faruk; Mutlu, Nilguen; Comunoglu, Nil; Koyuncu, Hasbey; Sarica, Kemal

doi:10.1016/j.juro.2009.09.076

Ethylene Glycol Induced Hyperoxaluria Increases Plasma and Renal Tissue Asymmetrical Dimethylarginine in Rats: A New Pathogenetic Link in Hyperoxaluria Induced Disorders

Atıf İçin Kopyala

Aydin H., Yencilek F., Mutlu N., Comunoglu N., Koyuncu H. H., Sarica K.

JOURNAL OF UROLOGY, cilt.183, sa.2, ss.759-764, 2010 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 183 Sayı: 2
Basım Tarihi: 2010
Doi Numarası: 10.1016/j.juro.2009.09.076
Dergi Adı: JOURNAL OF UROLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.759-764
İstanbul Üniversitesi Adresli: Hayır

Özet

Purpose: The pathogenesis of kidney stones remains elusive. There is some evidence that hyperoxaluria may effect vascular endothelium and many studies link renal stones to atherosclerosis. Also, renal vascular endothelial cells regulate proximal tubular epithelial cell function. We determined the effect of hyperoxaluria on plasma and tissue levels of asymmetrical dimethylarginine. The secondary aim was to determine the effect of verapamil on asymmetrical dimethylarginine.