Improvement of Coronary Flow Velocity Reserve with Telmisartan in Patients with Autosomal-Dominant Polycystic Kidney Disease

Alisir, Sabahat; Turkmen, Kültigin; Alpay, Nilufer; Elitok, Ali; Oflaz, Hüseyin; Uslu, Bora; Cimen, Arif; Kasikcioglu, Erdem; Tufan, Fatih; Ecder, Tevfik

doi:10.1097/smj.0b013e3181d80cae

Improvement of Coronary Flow Velocity Reserve with Telmisartan in Patients with Autosomal-Dominant Polycystic Kidney Disease

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Alisir S., Turkmen K., Alpay N., Elitok A., Oflaz H., Uslu B., ...More

SOUTHERN MEDICAL JOURNAL, vol.103, no.5, pp.409-413, 2010 (SCI-Expanded)

Publication Type: Article / Article
Volume: 103 Issue: 5
Publication Date: 2010
Doi Number: 10.1097/smj.0b013e3181d80cae
Journal Name: SOUTHERN MEDICAL JOURNAL
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.409-413
Istanbul University Affiliated: Yes

Abstract

Objectives: Endothelial dysfunction (ED) has been reported in patients with autosomal-dominant polycystic kidney disease (ADPKD). Coronary flow velocity reserve (CFVR) is a noninvasive test showing endothelial function of epicardial coronary arteries and coronary microcirculatory function. The aim of this study was to investigate the effect of the angiotensin receptor blocker, telmisartan, on CFVR in patients with ADPKD.