Improvement of Coronary Flow Velocity Reserve with Telmisartan in Patients with Autosomal-Dominant Polycystic Kidney Disease

Alisir S., Turkmen K., Alpay N., Elitok A., Oflaz H., Uslu B., ...More

SOUTHERN MEDICAL JOURNAL, vol.103, no.5, pp.409-413, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 103 Issue: 5
  • Publication Date: 2010
  • Doi Number: 10.1097/smj.0b013e3181d80cae
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.409-413
  • Istanbul University Affiliated: Yes


Objectives: Endothelial dysfunction (ED) has been reported in patients with autosomal-dominant polycystic kidney disease (ADPKD). Coronary flow velocity reserve (CFVR) is a noninvasive test showing endothelial function of epicardial coronary arteries and coronary microcirculatory function. The aim of this study was to investigate the effect of the angiotensin receptor blocker, telmisartan, on CFVR in patients with ADPKD.