Influence of genetic variations in ABCB1 on the clinical efficacy of ondansetron - A pharmacogenetic analysis of Pakistani population


Farhat K., Waheed A., Hussain A., Ismail M., Mansoor Q., Pasha A. K., ...More

JOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION, vol.65, no.9, pp.963-966, 2015 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 65 Issue: 9
  • Publication Date: 2015
  • Journal Name: JOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.963-966
  • Keywords: ATP-binding cassette subfamily B member 1 (ABCB1), Single nucleotide polymorphism, Genotyping, Ondansetron, P-glycoprotein, DRUG-RESISTANT EPILEPSY, POSTOPERATIVE NAUSEA, POLYMORPHISMS, ASSOCIATION
  • Istanbul University Affiliated: No

Abstract

Objective: To study the association of C1236T single-nucleotide polymorphisms of ABCB1 gene with non-responsiveness to antiemetic treatment in post-operative patients.