Akademik Veri Yönetim Sistemi
Literatür Eczacılık Bilimleri Dergisi, cilt.12, sa.1, ss.31-42, 2023 (Hakemli Dergi)
Ginkgo biloba L. is considered one of the oldest trees in the world and has been used for thousands of years for its variety of pharmacological effects. It is commonly known as ginkgo. Leaf extracts of this fossil tree have been standardized and patented under the name EGb761. EGb761 mainly consists of terpene trilactones which are unique to this species and flavone glycosides. It is sup- ported by scientific research that these chemical components are re- sponsible for the pharmacological effects of the tree.G. biloba L. has gained interest as a therapeutic plant for its favorable effects in cog- nitive impairment and neurodegenerative disorders like dementia. Its beneficial impacts on a wide range of pathological conditions, in- cluding cardiovascular health, asthma, psychiatric disorders, skin problems, and glaucoma as well as antioxidant, anti-inflammatory, anticancer and hepatoprotective activities, have been reported through experimental and clinical research. Ginkgo is generally well toler- ated but when combined with warfarin or other antiplatelet medica- tions, it can increase the risk of bleeding. This review mainly focuses on recent studies of pharmacological effects of G. biloba L. and in- dicates that G. biloba L. might be beneficial in the prevention and improvement of neurological, cardiovascular, pulmonary, ocular, metabolic, mental disorders also have anticancer and antimicrobial properties however further studies and clinical trials are necessary to confirm the safety and efficacy ofG. biloba L. in order to guide med- ical use.