Bilateral Acute Depigmentation of Iris (BADI) and Bilateral Acute Iris Transillumination (BAIT)-An Update

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Tuğal-Tutkun İ., Altan Ç.

Turkish Journal of Ophthalmology, vol.52, no.5, pp.342-347, 2022 (Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: 52 Issue: 5
  • Publication Date: 2022
  • Doi Number: 10.4274/tjo.galenos.2022.09552
  • Journal Name: Turkish Journal of Ophthalmology
  • Journal Indexes: Scopus
  • Page Numbers: pp.342-347
  • Keywords: Bilateral acute depigmentation of the iris, bilateral acute iris transillumination, moxifloxacin, ocular hypertension, pigment dispersion
  • Istanbul University Affiliated: Yes

Abstract

© 2022 by Turkish Ophthalmological Association Turkish Journal of Ophthalmology, published by Galenos Publishing House.Bilateral acute depigmentation of the iris (BADI) and bilateral acute iris transillumination (BAIT) are relatively new clinical entities characterized by acute pigment dispersion from the iris stroma or iris pigment epithelium, respectively. While BADI presents with diffuse or geographic areas of iris stromal depigmentation without transillumination, BAIT cases typically develop diffuse iris transillumination and mydriatic atonic pupils. Prolonged pigment dispersion and ocular hypertension are more common in BAIT. Although the exact etiopathogenesis is still unknown, moxifloxacin toxicity appears to be a probable/likely cause. The underlying cause of BADI or BAIT in patients who were not exposed to fluoroquinolone antibiotics remains unexplained. Systemic viral infections, including coronavirus disease 2019, may be the triggering event in several cases.