Biomarkers in Medicine, 2026 (SCI-Expanded, Scopus)
Objective: Cancer patients frequently present to emergency departments (EDs) with complex medical needs, requiring urgent clinical decisions. Identifying prognostic factors can help stratify patients into outcome groups and guide optimal care. Our aim was to analyze the clinical and laboratory characteristics of cancer patients in the ED and determine their relevance to prognosis across three outcome groups: Stable Discharge, Hospitalized Care, and Critical Care. Methods: This retrospective cohort study included 1,248 cancer patients admitted to a tertiary care ED between 2020 and 2022. Patients were divided into outcome groups based on their prognosis. Associations between clinical variables and outcomes were analyzed using ANOVA and Pearson Chi-Square tests. Results: Significant laboratory markers included elevated CRP and LDH levels, lower hemoglobin, and reduced oxygen saturation in Critical Care patients. Patients who underwent invasive procedures were more likely to belong to the Hospitalized Care Group or the Critical Care Group. Patients who required intravenous antibiotic therapy were more likely to fall into the Hospitalized Care Group. Conclusion: This study identifies key clinical and laboratory markers associated with cancer patient outcomes in the ED. These findings can assist clinicians in prioritizing care and improving patient management strategies.