Evaluation of apoptosis in cerebrospinal fluid of patients with severe head injury

Uzan M., Erman H., Tanriverdi T., Sanus G. Z., Kafadar A., Uzun H.

ACTA NEUROCHIRURGICA, vol.148, no.11, pp.1157-1164, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 148 Issue: 11
  • Publication Date: 2006
  • Doi Number: 10.1007/s00701-006-0887-1
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1157-1164
  • Istanbul University Affiliated: Yes


Objective. To determine whether sFas, caspase-3, proteins which propagate apoptosis, and bcl-2, a protein which inhibits apoptosis, would be increased in cerebrospinal fluid (CSF) in patients with severe traumatic brain injury (TBI) and to examine the correlation of sFas, caspase-3, and bcl-2 with each other and with clinical variables.