Time-level relationship for nitric oxide and the protective effects of aminoguanidine in experimental spinal cord injury


Soy O., Aslan O., Uzun H., Barut S., Igdem A., Belce A., ...Daha Fazla

ACTA NEUROCHIRURGICA, cilt.146, sa.12, ss.1329-1336, 2004 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 146 Sayı: 12
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1007/s00701-004-0343-z
  • Dergi Adı: ACTA NEUROCHIRURGICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1329-1336
  • İstanbul Üniversitesi Adresli: Hayır

Özet

Background. The secondary injury process following spinal cord trauma has been shown to involve different mechanisms such as excessive release of excitatory amino-acids, and induction of free radical induced lipid peroxidation. In this experimental study, the time-level relationship of the nitric oxide and the neuroprotective effects of aminoguanidine were investigated in a rat spinal cord trauma model.