Time-level relationship for nitric oxide and the protective effects of aminoguanidine in experimental spinal cord injury
ACTA NEUROCHIRURGICA, vol.146, no.12, pp.1329-1336, 2004 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 146 Issue: 12
- Publication Date: 2004
- Doi Number: 10.1007/s00701-004-0343-z
- Journal Name: ACTA NEUROCHIRURGICA
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.1329-1336
- Istanbul University Affiliated: No
Abstract
Background. The secondary injury process following spinal cord trauma has been shown to involve different mechanisms such as excessive release of excitatory amino-acids, and induction of free radical induced lipid peroxidation. In this experimental study, the time-level relationship of the nitric oxide and the neuroprotective effects of aminoguanidine were investigated in a rat spinal cord trauma model.