Aromatic Plant-Based Nanoemulsions or Gels and Their Biomedical Applications: A Microbiological and Pharmaceutical Botany Perspective


SELİM G., ARSLAN E. Ö., Koçyiğit M., DOĞRUÖZ GÜNGÖR N.

Smart Nanomaterials Technology, Springer, ss.287-319, 2026

  • Yayın Türü: Kitapta Bölüm / Araştırma Kitabı
  • Basım Tarihi: 2026
  • Doi Numarası: 10.1007/978-981-95-7409-4_12
  • Yayınevi: Springer
  • Sayfa Sayıları: ss.287-319
  • Anahtar Kelimeler: Antimicrobial activity, Aromatic plants, Biomedical applications, Gel formulations, Nanoemulsion
  • İstanbul Üniversitesi Adresli: Evet

Özet

Nanotechnology has become a game-changer in the biomedical sciences, providing new ways to improve drug delivery, control infections, and heal wounds. In this context, nanoemulsions and hydrogels have attracted significant interest, owing to their distinctive physicochemical properties and biocompatibility. Nanoemulsions, which are made up of tiny droplets of liquids that don’t mix with each other and are held together by surfactants, have better solubility, stability, and permeability. This makes them great for use in the mouth, on the skin, in the eyes, in the nose, and in the veins. Hydrogels, on the other hand, are polymeric networks that are hydrophilic, hold a lot of water, are structurally similar to natural tissues, and are very biocompatible. They create a wet environment for tissue regeneration and let drugs be released in a controlled way, which makes the treatment more effective. Chitosan-based hydrogels are very useful because they stick to the skin and last a long time. Combining these two systems into hybrid formulations called nanoemulgels makes them even more effective by making them thicker, able to hold more drugs, and able to stay on the skin longer. Experimental studies underscore their biomedical potential: lavender nanoemulsions combined with chitosan hydrogels exhibited enhanced antiviral efficacy against herpes simplex virus type 1; psoralen formulations incorporating fennel and clove oil nanoemulsions improved transdermal delivery in psoriasis and vitiligo treatment; Pituranthos tortuosus nanoemulsion gels expedited wound healing; and clove-cinnamon oil nanoemulgels demonstrated significant antimicrobial and antibiofilm activity against resistant pathogens. These results underscore the function of nanoemulsions and gels not merely as delivery mechanisms but also as dynamic therapeutic platforms that utilize the inherent bioactivity of essential oils derived from aromatic plants. These systems combine traditional herbal medicine with modern nanotechnology to provide solutions for treating infectious diseases, speeding up wound healing, and speeding up tissue regeneration. In general, aromatic plant-based nanoemulsions and hydrogels are promising new approaches in microbiology and pharmaceutical botany that connect natural resources with biomedical innovation.