18th International Nanoscience and Nanotechnology Conference, İstanbul, Türkiye, 26 - 28 Ağustos 2024, ss.49
Acoustofluidics is a widely used cell
manipulation technique in microfluidic systems. In these systems, surface
acoustic waves (SAWs) generated on a piezoelectric substrate are used to
control the movement of biological particles. SAWs operate in a contactless
manner and are biocompatible, eliminating the need for labeling biological
samples[1]. The surface
acoustic wave is typically generated on the piezoelectric substrate through
interdigitated transducers, which is a common method employed in acoustofluidic
systems. This study introduces an innovative approach to acoustofluidic systems
using piezoelectric phononic crystals. Integrated transducers and piezoelectric
phononic crystals were fabricated using lithographic methods on YX-128° LiNbO3,
operating at a frequency of 85 MHz. The microchannel, which has a width of 100
microns and was produced using soft lithography techniques, was bonded onto
YX-128° LiNbO3. Observations
revealed that 5 µm diameter polystyrene particles were patterned at λ/2 nodes
within the microchannel. This novel approach holds significant potential to
revolutionize cell manipulation in lab-on-a-chip technology in the future.