Relationship between ciprofloxacin resistance and extended-spectrum beta-lactamase production in Escherichia coli and Klebsiella pneumoniae strains

Tolun, V; Kucukbasmaci, Kenan; Torumkuney-Akbulut, D; Catal, C; Ang-Kucuker, M; Ang, O

doi:10.1111/j.1469-0691.2004.00723.x

Relationship between ciprofloxacin resistance and extended-spectrum beta-lactamase production in Escherichia coli and Klebsiella pneumoniae strains

Atıf İçin Kopyala

Tolun V., Kucukbasmaci O., Torumkuney-Akbulut D., Catal C., Ang-Kucuker M., Ang O.

CLINICAL MICROBIOLOGY AND INFECTION, cilt.10, sa.1, ss.72-75, 2004 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 10 Sayı: 1
Basım Tarihi: 2004
Doi Numarası: 10.1111/j.1469-0691.2004.00723.x
Dergi Adı: CLINICAL MICROBIOLOGY AND INFECTION
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.72-75
İstanbul Üniversitesi Adresli: Evet

Özet

Resistance to fluoroquinolones has increased markedly since their introduction. Mechanisms of resistance to any antibiotic class might play a role in resistance to an unrelated antibiotic class. This study evaluated the relationship between extended-spectrum beta-lactamase (ESBL) production and ciprofloxacin resistance in Escherichia coli and Klebsiella pneumoniae strains isolated as causative agents of urinary tract infection. ESBL-producing strains were significantly more frequent among ciprofloxacin-resistant E. coli strains than among ciprofloxacin-susceptible E. coli strains (p = 0.015), but the difference was not significant among K. pneumoniae strains (p = 0.276).