GC-MS characterization of the essential oil from <i>Teucrium kotschyanum</i> Poech (Lamiaceae) and its antimicrobial assessment


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Gürer Ç. Ü., Tütüniş S., Gülsoytoplan G., İŞCAN G., DEMİRCİ B., TAN N.

RECORDS OF NATURAL PRODUCTS, vol.20, no.3, 2026 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 20 Issue: 3
  • Publication Date: 2026
  • Doi Number: 10.25135/rnp.2512.3750
  • Journal Name: RECORDS OF NATURAL PRODUCTS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, ABI/INFORM, EMBASE, Academic Search Ultimate (EBSCO), Biomedical Reference Collection: Corporate Edition (EBSCO)
  • Keywords: antimicrobial activity, essential oil, GC-MS, Lamiaceae, Teucrium kotschyanum Poech
  • Open Archive Collection: AVESIS Open Access Collection
  • Istanbul University Affiliated: Yes

Abstract

The genus Teucrium L., a member of the Lamiaceae family, is represented by approximately 36 species in T & uuml;rkiye. In this study, the essential oil composition of the aerial parts of Teucrium kotschyanum Poech collected from I(center dot)zmir (& Ouml;demi,s) was investigated by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) for the first time. The major compounds were identified as germacrene D (20.0%), alpha-cadinol (6.9%), beta-bourbonene (6.6%), hexadecanoic acid (6.6%), delta-cadinene (5.9%) and manool (4.1%). The antibacterial and antifungal activities of the essential oil were evaluated against six bacteria and six fungi using the microdilution broth method. The essential oil exhibited limited antimicrobial activity, with the highest efficacy observed against Candida utilis (MIC: 125 mu g/mL) and the lowest against Staphylococcus epidermidis and Salmonella typhimurium (MIC: 2000 mu g/mL).