Multiple atypical recurrent meningiomas 13 years after radiotherapy for unilateral retinoblastoma: case report and review of the literature

Aras Y. , Akcakaya M. O. , Aydoseli A. , Meral R., Kiris T.

NEUROLOGIA I NEUROCHIRURGIA POLSKA, vol.47, no.1, pp.80-85, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 47 Issue: 1
  • Publication Date: 2013
  • Doi Number: 10.5114/ninp.2013.32932
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.80-85
  • Keywords: radiotherapy, meningioma, radiation-induced tumour, secondary brain neoplasms in children, retinoblastoma, RADIATION-INDUCED MENINGIOMAS, INTRACRANIAL MENINGIOMAS, IRRADIATION, EXPERIENCE, CHILDHOOD, THERAPY, GLIOMAS, SURVIVORS, CHILDREN, TUMORS


Radiotherapy is an important treatment modality for intracranial malignancies. Improved survival rates were achieved via a combination of surgery, chemotherapy and radiotherapy. On the other hand, improved survival rates made long-term complications of radiotherapy more apparent. Secondary neoplasms due to cranial irradiation are encountered more commonly in neurosurgical practice. Radiation-induced meningiomas are recognized as a common late complication of radiotherapy. However, radiation-induced meningiomas after radiotherapy for retinoblastoma have been reported rarely. Herein we report a patient who harboured multiple meningiomas 13 years after radiotherapy for unilateral retinoblastoma, which were recurrent despite surgical removal and chemotherapy.