CYTOTOXIC AND ANTIBACTERIAL SESQUITERPENES FROM INULA-GRAVEOLENS


TOPCU G., OKSUZ S., SHIEH H., CORDELL G., PEZZUTO J., BOZOKJOHANSSON C.

PHYTOCHEMISTRY, vol.33, no.2, pp.407-410, 1993 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 2
  • Publication Date: 1993
  • Doi Number: 10.1016/0031-9422(93)85529-z
  • Title of Journal : PHYTOCHEMISTRY
  • Page Numbers: pp.407-410

Abstract

A further study on the aerial parts of Inula graveolens afforded a new eudesmanolide, 11,13-dihydroivalin and four known sesquiterpene lactones, ivalin, inuviscolide, 8-epi-inuviscolide, 8-epi-xanthatin-1beta,5beta-epoxide, in addition to the previously isolated compounds. The structures were established by spectral methods and the compounds were evaluated for their cytotoxic and antibacterial activity.