No Effect of the IGF-1 Gene rs35767 and rs17032362 Polymorphisms in the Etiology of Idiopathic Short Stature


Tekcan D., Bas F., Atalar F., Aydin B. K. , Akan G., Tarhan T., ...More

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, vol.120, no.7, pp.395-400, 2012 (SCI-Expanded) identifier identifier identifier

Abstract

Objective: Idiopathic short stature (ISS) refers to pathophysiologically wide and heterogeneous range of disorders, which are considered to involve defects in growth hormone (GH)-insulin like growth factor-1 (IGF-1) axis. This study was designed to evaluate GH- IGF-1 axis and investigate IGF-1 gene polymorphisms in ISS.