No Effect of the IGF-1 Gene rs35767 and rs17032362 Polymorphisms in the Etiology of Idiopathic Short Stature

Tekcan, D.; Bas, FİRDEVS; Atalar, FATMAHAN; Aydin, B.; Akan, G.; Tarhan, T.; Bundak, Rüveyde; Darendeliler, Fatma

doi:10.1055/s-0032-1314810

No Effect of the IGF-1 Gene rs35767 and rs17032362 Polymorphisms in the Etiology of Idiopathic Short Stature

Tekcan D., Bas F., Atalar F., Aydin B. K., Akan G., Tarhan T., ...Daha Fazla

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, cilt.120, sa.7, ss.395-400, 2012 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 120 Sayı: 7
Basım Tarihi: 2012
Doi Numarası: 10.1055/s-0032-1314810
Dergi Adı: EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.395-400
İstanbul Üniversitesi Adresli: Evet

Özet

Objective: Idiopathic short stature (ISS) refers to pathophysiologically wide and heterogeneous range of disorders, which are considered to involve defects in growth hormone (GH)-insulin like growth factor-1 (IGF-1) axis. This study was designed to evaluate GH- IGF-1 axis and investigate IGF-1 gene polymorphisms in ISS.